2. Signaling Pathways
  3. Membrane Transporter/Ion Channel
    Neuronal Signaling
  4. Calcium Channel
  5. Calcium Channel Agonist

Calcium Channel Agonist

Calcium Channel Agonists (12):

Cat. No. Product Name Effect Purity
  • HY-10588
    Bay K 8644
    		Agonist 98.62%
    Bay K 8644 ((±)-Bay K 8644) is a racemate consisting of two isomers (R)-(+)-Bay-K-8644 and (S)-(-)-Bay-K-8644. Bay K 8644 is a L-type Ca2+ channel agonist with an EC50 of 17.3 nM. Bay K 8644 increases Ca2+ influx through sarcolemmal Ca2+ channels by increasing the open time of the channel. Bay K 8644 has vasoconstrictive effects.
  • HY-113308A
    Taurolithocholic acid sodium salt
    		Agonist 98.02%
    Taurolithocholic acid sodium salt, a potent cholestatic agent, is a potent Ca2+ agonist.
  • HY-15124
    (S)-(-)-Bay-K-8644
    		Agonist 98.81%
    (S)-(-)-Bay-K-8644 is an agonist of L-type Ca2+ channel. (S)-(-)-Bay-K-8644 activates Ba2+ currents (IBa) (EC50=32 nM).
  • HY-103307
    FPL64176
    		Agonist 99.81%
    FPL64176, a nondihydropyridine compound, is a potent agonist of L-type Ca2+ channels with an EC50 value of 16 nM.
  • HY-12498
    GV-58
    		Agonist 99.51%
    GV-58 is a novel N- and P/Q-type calcium (Ca2+) channel agonist with EC50s of 7.21 and 8.81 μM, respectively. GV-58 slows the deactivation of channels, resulting in a large increase in presynaptic Ca2+ entry during activity. GV-58 can be used in lambert-eaton myasthenic syndrome (LEMS) research.
  • HY-41076
    Ca2+ channel agonist 1
    		Agonist 99.71%
    Ca2+ channel agonist 1 is an agonist of N-type Ca2+ channel and an inhibitor of Cdk2, with EC50s of 14.23 μM and 3.34 μM, respectively, and is used as a potential treatment for motor nerve terminal dysfunction.
  • HY-113308AS
    Taurolithocholic acid-d4 sodium
    		Agonist
    Taurolithocholic acid-d4 (sodium) is the deuterium labeled Taurolithocholic acid (sodium salt). Taurolithocholic acid sodium salt, a potent cholestatic agent, is a potent Ca2+ agonist[1].
  • HY-113308AS2
    Taurolithocholic acid-d4-1 sodium
    		Agonist
    Taurolithocholic acid-d4-1 (sodium) is the deuterium labeled Taurolithocholic acid. Taurolithocholic acid sodium salt, a potent cholestatic agent, is a potent Ca2+ agonist[1].
  • HY-113308S
    Taurolithocholic acid-d5
    		Agonist
    Taurolithocholic acid-d5 is deuterium labeled Taurolithocholic acid.
  • HY-113308S1
    Taurolithocholic acid-d4
    		Agonist
    Taurolithocholic acid-d4 is deuterium labeled Taurolithocholic acid.
  • HY-113308AS1
    Taurolithocholic Acid-d5 sodium
    		Agonist
    Taurolithocholic Acid-d5 (sodium) is the deuterium labeled Taurolithocholic acid sodium salt. Taurolithocholic acid sodium salt, a potent cholestatic agent, is a potent Ca2+ agonist[1][2].
  • HY-P5114
    Maurocalcine
    		Agonist
    Maurocalcine is an agonist of ryanodine receptor (RyR) channel types 1, 2 and 3 with cellular permeability. Maurocalcine induces [3H]ryanodine binding on RyR1 with an EC50 value of 2558 nM. Maurocalcine exhibits a apparent affinity of 14 nM for RyR2. Maurocalcine can be applied to in vivo cell tracking or other cell imaging techniques.